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Therapeutics and Clinical Risk Management, 20, 151-160

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Retreatment with peginterferon plus ribavirin should be considered for non-responders or relapsers who have significant fibrosis or cirrhosis and who have undergone previous regimens of treatment using non-pegylatedinterferon (II-3) 18

Furthermore, because hospitals can resell these drugs at a markup, they are incentivized to purchase more expensive drugs that receive larger discounts, creating demand for more expensive drugs and thus further upward pressure on prices